There are 2 alcohol/food/lifestyle interactions with meloxicam.
Moderate
Alcohol (Ethanol) Meloxicam
Moderate Drug Interaction
Ask your doctor before using meloxicam together with ethanol (alcohol). Do not drink alcohol while taking meloxicam. Alcohol can increase your risk of stomach bleeding caused by meloxicam. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Major
Meloxicam High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
NSAIDs - fluid retention
Fluid retention and edema have been reported in association with the use of nonsteroidal anti-inflammatory drugs (NSAIDs), including some topical formulations. NSAIDs (including topicals) can lead to new onset of hypertension or worsening of preexisting hypertension, either of which can contribute to the increased incidence of cardiovascular events. NSAIDs should be used with caution in patients with preexisting fluid retention, hypertension, or history of heart failure. NSAIDs should be avoided in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failure; if an NSAID is used in such patients, they should be monitored for signs of worsening heart failure. Blood pressure and cardiovascular status should be monitored closely during the initiation of NSAID treatment and throughout the course of therapy.
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Meloxicam drug interactions
There are 468 drug interactions with meloxicam.
Meloxicam disease interactions
There are 10 disease interactions with meloxicam which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
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Drug Interaction Classification
Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
---|---|
Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Unknown | No interaction information available. |
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